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Hypoxia

Hypoxia
 

The development of complex anatomical and physiological systems to maintain oxygen homeostasis was an essential process in the evolution of metazoans. Hypoxia, defined as an insufficient oxygen supply to tissues, elicits a cellular response that hinges on the stabilization of hypoxia-inducible factors (HIFs). These transcription factors are subsequently able to accumulate in the nucleus and bind to DNA at “hypoxia response elements” (HREs) and subsequently drive either the expression (or, perhaps indirectly, the repression) of hundreds of genes.

Highlighted Products

      
HIF1 alpha antibody

HIF1 alpha antibody (GTX628480)

 
HIF1 beta antibody

HIF1 beta antibody (GTX128795)

HIF2 alpha antibody

HIF2 alpha antibody (GTX632015)

 
 
 
CAIX antibody

CAIX antibody (GTX70020)

 
Heme Oxygenase 1 antibody

Heme Oxygenase 1 antibody (GTX101147)

  
PHD2 antibody

PHD2 antibody (GTX132293)

 
 
 
PKM antibody

PKM antibody (GTX107977)

  
MMP2 antibody

MMP2 antibody (GTX104577)

 
VEGF antibody

VEGF antibody (GTX102643)

  
 
 
VE-cadherin antibody

VE-cadherin antibody (GTX633705)

 
mTOR antibody

mTOR antibody (GTX101557)

 
AKT (pSer473) antibody

AKT (pSer473) antibody (GTX128414)

 
 
 
PHD1 antibody

PHD1 antibody (GTX123033)

 
PHD4 antibody

PHD4 antibody (GTX116582)

 
VHL antibody

VHL antibody (GTX101087)

 
 
 
PD-L1 antibody

PD-L1 antibody (GTX104763)

   
     

 

 

Pathways

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Literature

Poster - Cancer Signaling

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Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
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Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature

Poster - Hypoxia Regulation

Download the latest version of GeneTex's hypoxia regulation poster
Literature

Flyer - Hypoxia Markers

Download the latest version of GeneTex's hypoxia markers poster
Literature

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature

Poster - Hypoxia Regulation

Download the latest version of GeneTex's hypoxia regulation poster
Literature

Flyer - Hypoxia Markers

Download the latest version of GeneTex's hypoxia markers poster