Thrombosis refers to clot formation within the vasculature that impedes the normal flow of blood. Clots can form in either arteries or veins. Arterial thrombi are often due to atherosclerosis, which is characterized by plaques that are highly thrombogenic when they rupture. Venous thrombi can result from vessel damage or disease, immobility, obesity, clotting disorders, certain medications, and other medical conditions. A particularly dangerous, and often lethal, result of thrombosis occurs when a clot breaks free and causes either an embolic stroke or a pulmonary embolism. |