Figure 1. The EV71 virion
Figure 1. The EV71 virion
Discovered in 1969, human enterovirus 71 (EV71) is the causative agent of hand-foot-and-mouth disease (HFMD) in young children, with a subset of patients developing more severe neurological disease that can result in death. Though epidemics have become more numerous since 1997, there are still no effective therapies or an established vaccine. Clearly, further research into the biology of this virus is of the utmost importance.
 
As a member of the genus Enterovirus in the family Picornaviridae, EV71 has a positive-stranded RNA genome coding for a 2,194 amino acid polyprotein, which is subsequently processed into four structural (VP1-VP4) and seven non-structural (2A, 2B, 2C, 3A, 3B, 3C, 3D) proteins. Identifying the specific functions of these proteins and their interactions with host factors will provide crucial information regarding EV71-associated neural pathogenesis and viral replication.
 
GeneTex is proud to offer an outstanding selection of antibodies for EV71 research. Please see the highlighted antibodies below or click here to see our latest EV71 research products.
 
Figure 2. The EV71 genome codes for a single polyprotein that is processed into 11 mature proteins.
Figure 2. The EV71 genome codes for a single polyprotein that is processed into 11 mature proteins.
Figure 2. The EV71 genome codes for a single polyprotein that is processed into 11 mature proteins.
 

Featured Products

Recombinant Citation-Support Orthogonal Validation Protein Overexpression 

Enterovirus 71 VP1 antibody [HL1928] (GTX637687)

Enterovirus 71 VP1 antibody [HL1928] (GTX637687)

RecombinantOrthogonal Validation
Enterovirus 71 VP1 antibody [HL1929] (GTX637688)

Enterovirus 71 VP1 antibody [HL1929] (GTX637688)

RecombinantOrthogonal Validation
Sandwich ELISA

Sandwich ELISA

Capture: Enterovirus 71 VP1 antibody [HL1929] (GTX637688)
Detection: Enterovirus 71 VP1 antibody [HL1928] (GTX637687)
RecombinantOrthogonal Validation
 
Enterovirus 71 VP1 antibody (GTX132339)

Enterovirus 71 VP1 antibody (GTX132339)

Citation-SupportOrthogonal Validation
Enterovirus 71 VP2 antibody (GTX132340)

Enterovirus 71 VP2 antibody (GTX132340)

Citation-SupportOrthogonal Validation
Enterovirus 71 2B antibody (GTX132343)

Enterovirus 71 2B antibody (GTX132343)

Citation-Support
 
Enterovirus 71 3AB antibody (GTX132344)

Enterovirus 71 3AB antibody (GTX132344)

Citation-Support
     
Cat. No. Product Name Host & Clonality  Applications  
GTX132340 Enterovirus 71 VP2 antibody Rb pAb WB, ICC/IF, IHC-P Citation-Support Orthogonal Validation
GTX132341 Enterovirus 71 VP3 antibody Rb pAb WB, ICC/IF Citation-Support
GTX637687 Enterovirus 71 VP1 antibody [HL1928] Rec Rb mAb WB, ELISA, Sandwich ELISA Recombinant Orthogonal Validation
GTX637688 Enterovirus 71 VP1 antibody [HL1929] Rec Rb mAb WB, ELISA, Sandwich ELISA Recombinant Orthogonal Validation
GTX633390 Enterovirus 71 VP1 antibody [GT185] Ms mAb WB, ELISA Citation-Support Orthogonal Validation
GTX633583 Enterovirus 71 VP1 antibody [GT9512] Ms mAb WB, ELISA  
GTX132338 Enterovirus 71 VP1 antibody Rb pAb WB, ICC/IF, IHC-P Citation-Support Orthogonal Validation
GTX132339 Enterovirus 71 VP1 antibody Rb pAb WB, ICC/IF, IHC-P Citation-Support Orthogonal Validation
GTX132600 Enterovirus 71 VP1 antibody Rb pAb WB  
GTX132343 Enterovirus 71 2B antibody Rb pAb WB, IHC-P Citation-Support
GTX132354 Enterovirus 71 2C antibody Rb pAb WB Citation-Support
GTX132344 Enterovirus 71 3AB antibody Rb pAb WB, IHC-P Citation-Support
GTX630191 Enterovirus 71 3C antibody [B3] Ms mAb WB, FACS Citation-Support Protein Overexpression
GTX132357 Enterovirus 71 3C antibody Rb pAb WB Citation-Support
GTX630193 Enterovirus 71 3D antibody [4] Ms mAb WB, ICC/IF, IP Citation-Support
GTX132355 Enterovirus 71 3CD antibody Rb pAb WB Citation-Support
GTX132356 Enterovirus 71 3CD antibody Rb pAb WB  
GTX124261 Enterovirus 71 antibody Rb pAb WB, ICC/IF, IHC-P, ELISA Citation-Support

 

GTX132340 GTX132341 GTX132339 GTX132343 GTX132354 GTX132344 GTX630191 GTX132356 GTX630193