Figure 1. The EV71 virion

 

Discovered in 1969, human enterovirus 71 (EV71) is the causative agent of hand-foot-and-mouth disease (HFMD) in young children, with a subset of patients developing more severe neurological disease that can result in death. Though epidemics have become more numerous since 1997, there are still no effective therapies or an established vaccine. Clearly, further research into the biology of this virus is of the utmost importance.

 

As a member of the genus Enterovirus in the family Picornaviridae, EV71 has a positive-stranded RNA genome coding for a 2,194 amino acid polyprotein, which is subsequently processed into four structural (VP1-VP4) and seven non-structural (2A, 2B, 2C, 3A, 3B, 3C, 3D) proteins. Identifying the specific functions of these proteins and their interactions with host factors will provide crucial information regarding EV71-associated neural pathogenesis and viral replication.

 

GeneTex is proud to offer an outstanding selection of antibodies for EV71 research. Please see the highlighted antibodies below or click here to see our latest EV71 research products. 

 

Figure 2. The EV71 genome codes for a single polyprotein that is processed into 11 mature proteins.

Featured Products

 

 

Enterovirus 71 VP1 antibody [HL1928] GTX637687	Enterovirus 71 VP1 antibody [HL1929] GTX637688	Sandwich ELISA Capture: Enterovirus 71 VP1 antibody [HL1929] GTX637688 Detection: Enterovirus 71 VP1 antibody [HL1928] GTX637687	Enterovirus 71 VP1 antibody GTX132339

Enterovirus 71 VP2 antibody GTX132340	Enterovirus 71 2B antibody GTX132343	Enterovirus 71 3AB antibody GTX132344

Cat. No. Product Name Clonality Applications GTX132340 Enterovirus 71 VP2 antibody Rb pAb WB, ICC/IF, IHC-P GTX132341 Enterovirus 71 VP3 antibody Rb pAb WB, ICC/IF GTX637687 Enterovirus 71 VP1 antibody [HL1928] Rec Rb mAb WB, ELISA, Sandwich ELISA GTX637688 Enterovirus 71 VP1 antibody [HL1929] Rec Rb mAb WB, ELISA, Sandwich ELISA GTX633390 Enterovirus 71 VP1 antibody [GT185] Ms mAb WB, ELISA GTX633583 Enterovirus 71 VP1 antibody [GT9512] Ms mAb WB, ELISA GTX132338 Enterovirus 71 VP1 antibody Rb pAb WB, ICC/IF, IHC-P GTX132339 Enterovirus 71 VP1 antibody Rb pAb WB, ICC/IF, IHC-P GTX132600 Enterovirus 71 VP1 antibody Rb pAb WB GTX132343 Enterovirus 71 2B antibody Rb pAb WB, IHC-P GTX132354 Enterovirus 71 2C antibody  Rb pAb WB GTX132344 Enterovirus 71 3AB antibody Rb pAb WB, IHC-P GTX630191 Enterovirus 71 3C antibody [B3] Ms mAb WB, FACS GTX132357 Enterovirus 71 3C antibody Rb pAb WB GTX630193 Enterovirus 71 3D antibody [4] Ms mAb WB, ICC/IF, IP GTX132355 Enterovirus 71 3CD antibody Rb pAb WB GTX132356 Enterovirus 71 3CD antibody Rb pAb WB GTX124261 Enterovirus 71 antibody Rb pAb WB, ICC/IF, IHC-P, ELISA