Cancer Tissue Gallery- GTX639933

Claudin 3 antibody [HMV309] HistoMAXTM

 

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Adrenal gland – CLDN3 negative adrenocortical adenoma

Adrenal gland – CLDN3 negative pheochromocytoma

Breast – Invasive breast cancer of no special type (NST) with strong CLDN3 staining of tumor cells

Breast – Invasive lobular breast cancer with a moderate to strong CLDN3 staining of tumor cells

       

Colon – Colorectal adenocarcinoma with strong CLDN3 immunostaining of tumor cells

Esophagus – Adenocarcinoma with strong CLDN3 immunostaining of tumor cells

Esophagus – CLDN3 negative squamous cell carcinoma

Esophagus – Adenocarcinoma with only a faint membranous CLDN3 staining of few tumor cells

       

Kidney – Chromophobe renal cell carcinoma with a weak CLDN3 staining of few tumor cells

Kidney – CLDN3 negative clear cell carcinoma

Kidney – Clear cell renal cell carcinoma showing a weak strong CLDN3 staining of tumor cells

Kidney – Papillary renal cell carcinoma with strong CLDN3 immunostaining of tumor cells

       

Liver – Cholangiocellular carcinoma with intense CLDN3 positivity of all tumor cells

Liver – Hepatocellular carcinoma with strong CLDN3 staining of tumor cells

Lung – Adenocarcinoma with strong CLDN3 positivity of all tumor cells

Lymph node – CLDN3 negative Hodgkin’s lymphoma

       

Ovary – Clear cell carcinoma with strong CLDN3 staining of tumor cells

Ovary – Serous high-grade carcinoma with strong CLDN3 staining of tumor cells

Pancrea – Adenocarcinoma of the papilla Vaterii with strong CLDN3 staining of tumor cells

Pancreas – CLDN3 negative ductal adenocarcinoma. CLDN3 positivity is seen in adjacent non-neoplastic cells

       

Pancreas – CLDN3 negative ductal adenocarcinoma

Pancreas – Ductal adenocarcinoma with faint CLDN3 staining of tumor cells

Pancreas – Neuroendocrine tumor showing a strong CLDN3 staining of 100_ of tumor cells

Penis – CLDN3 negative squamous cell carcinoma

       

Pharynx – CLDN3 negative squamous cell carcinoma

Prostate – Adenocarcinoma (Gleason 3+3=6) with strong CLDN3 staining of tumor cells

Prostate – Adenocarcinoma (Gleason 5+5=10) with strong CLDN3 staining of tumor cells. Staining is markedly stronger than in intermingled non-neoplastic atrophic cells

Salivary gland – Warthin tumor with a moderate CLDN3 staining of tumor cells

       

Salivary gland – Warthin tumor with a weak to moderate CLDN3 staining of tumor cells. In addition, a strong staining occurs in cell groups within lymphatic tissue

Salivary gland – Warthin tumor with faint CLDN3 staining of luminal membranes of tumor cells. In addition, a strong staining occurs in cell groups within lymphatic tissue

Stomach – CLDN3 negative gastric adenocarcinoma (diffuse type)

Stomach – CLDN3 negative gastrointestinal stromal tumor (GIST)

       

Stomach – Gastric adenocarcinoma (diffuse type) with strong CLDN3 staining of tumor cells

Stomach – Gastric adenocarcinoma (intestinal type) with intense CLDN3 positivity of tumor cells

Stomach – Gastric adenocarcinoma (intestinal type) with strong CLDN3 positivity of most tumor cells

Stomach – CLDN3 negative gastrointestinal stromal tumor (GIST)

       

Testis – CLDN3 negative embryonal carcinoma

Testis – CLDN3 negative seminoma

Urinary bladder – CLDN3 negative muscle-invasive urothelial carcinoma

Urinary bladder – Muscle-invasive urothelial carcinoma with strong CLDN3 positivity of tumor cells

       

Uterus, cervix – Adenocarcinoma with strong CLDN3 immunostaining of most tumor cells

Vagina – Squamous cell carcinoma with strong CLDN3 positivity of all tumor cells

   

 

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