Cancer Metabolism

Nearly a century ago, Otto Warburg found that cancer cells can shift their energy production to aerobic glycolysis instead of the more efficient oxidative phosphorylation. An emerging hallmark of many cancers is their metabolic plasticity, as rewiring of cancer cells' metabolic fluxes is essential for their proliferative and invasive agenda. With increasing understanding of these alterations, researchers are identifying features of tumor metabolism that can be used for novel diagnostic, prognostic, and therapeutic opportunities.

Highlighted Products
   
IDH1 antibody

IDH1 antibody  (GTX629818)

IDH2 antibody

IDH2 antibody  (GTX628487)

 
LDHA antibody

LDHA antibody (GTX101416)

Hexokinase 1 antibody

Hexokinase 1 antibody (GTX105248)

PKM antibody

PKM antibody (GTX107977)

  
Pyruvate Dehydrogenase E1 alpha antibody

Pyruvate Dehydrogenase E1 alpha antibody (GTX104015)