Nearly a century ago, Otto Warburg found that cancer cells can shift their energy production to aerobic glycolysis instead of the more efficient oxidative phosphorylation. An emerging hallmark of many cancers is their metabolic plasticity, as rewiring of cancer cells' metabolic fluxes is essential for their proliferative and invasive agenda. With increasing understanding of these alterations, researchers are identifying features of tumor metabolism that can be used for novel diagnostic, prognostic, and therapeutic opportunities.

IDH1 antibody GTX629818	IDH2 antibody GTX628487	LDHA antibody GTX101416	Hexokinase 1 antibody GTX105248

PKM antibody GTX107977	Pyruvate Dehydrogenase E1 alpha antibody GTX104015