Karagoz et al., 2023

 

Monkeypox (Mpox) virus (MPXV) is the causative agent of the zoonotic disease known as Mpox, which infects both humans and animals. First detected in monkeys in 1959, the first human case was diagnosed 12 years later. MPXV, an orthopoxvirus in the family Poxviridae, has a brick-shaped or oval morphology and contains a linear, double-stranded DNA of 197 kb encoding ~181 proteins. Its genome consists of a conserved central region, two terminal variable regions, and two inverted terminal repeats (ITRs), which is similar to other orthopoxviruses. The conserved region is responsible for transcription, replication, and virion assembly while the variable regions differ between orthopoxviruses and produce proteins involved in virulence and host range.

 

See All Related Products

 

 

Featured Products

 

Mpox virus F13L antibody [HL2637]

Mpox virus D8L antibody [HL2950]

Mpox virus A29L antibody [HL2527]

Mpox virus A4L antibody [HL2555]

       

 

 

Mpox virus B6R antibody [HL3102]

     
       

 

 

References:

  1. J Infect Public Health. 2023 Apr;16(4):531-541.
  2. Signal Transduct Target Ther. 2023 Dec 27;8(1):458.
  3. EBioMedicine. 2023 Jan:87:104424.