Mitochondrial Fission/Fusion and Cardiovascular Disease

Mitochondria are dynamic organelles involved in a multitude of cellular metabolic processes beyond just ATP generation. They are capable of undergoing fission or fusion depending on environmental conditions and perturbation of these homeostatic processes has been linked to cardiovascular (CV) disease (1). Prevention of abnormal mitochondrial fission is being investigated as a potential therapeutic approach for CV disease management.

GeneTex is expanding its catalog of reagents for mitochondrial research with the addition of three recombinant rabbit antibodies against mitochondrial fission factor (MFF) (see two of these below), which are validated for several applications. These antibodies join reagents detecting other fission factors including dynamin-related protein 1 (DRP1) and mitochondrial fission 1 protein (FIS1) (see below). To learn more about GeneTex’s antibodies for mitochondria research, please click here or visit www.genetex.com.