Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of human ApoE expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
RRID
AB_2887968
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
FACS analysis of HepG2 cells using GTX60446 Apolipoprotein E antibody [1H4]. Green : Apolipoprotein E Purple : negative control
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GTX60446 ELISA Image
ELISA analysis of antigen using GTX60446 Apolipoprotein E antibody [1H4].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng
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GTX60446 WB Image
WB analysis of HEK293 (1) and ApoE (AA: 20-267)-hIgGFc transfected HEK293 (2) cell lysate using GTX60446 Apolipoprotein E antibody [1H4].
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GTX60446 IHC-P Image
IHC-P analysis of liver cancer tissue (left) and brain tissue (right) using GTX60446 Apolipoprotein E antibody [1H4].