GeneTex

  • Country / Location Selection

United States (US)

CD18 antibody [MEM-148] (FITC)

Cat. No. GTX75790

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-148

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
50 μg ($339)
See all CD18 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Product Note

This antibody recognizes an epitope on the human CD18 molecule that is hidden in the CD11/CD18 heterodimer on resting cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peripheral blood mononuclear cells.

Purification

Protein A purified

Conjugation

Fluorescein isothiocyanate (FITC)

RRID

AB_377034

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 2 , CD18 , LAD , LCAMB , LFA-1 , MAC-1 , MF17 , MFI7

Cellular Localization

Cell membrane

Background

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Database

Research Area

REFERENCE

Clone Reference

Li N et al. J Immunol 2013; 190 (8):4371-81 Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation.
Submit a Reference

REVIEW

There are currently no reviews for CD18 antibody [MEM-148] (FITC) (GTX75790). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339