Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin).
We do not recommend use of this product for Dog samples.
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Leukocytes of a patient suffering from a LGL-type leukemia.
Purification
Purified by size-exclusion chromatography
Conjugation
Allophycocyanin (APC)
RRID
AB_11166700
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
CD18 , ITGB2 , LAD , LCAMB , LFA1 , MAC1 , MF17 , MFI7 , integrin subunit beta 2 , Integrin beta2
Cellular Localization
Membrane
Background
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Database
Research Area