GeneTex

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United States (US)

CD66e antibody

Cat. No. GTX19128

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB

Reactivity

 Human
Package
50 μg ($519)
See all CD66e products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Immunogen Sequence: GI # 11386171, sequence 460-600 Recombinant carcinoembryonic antigen-related cell adhesion molecule 5

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

carcinoembryonic antigen related cell adhesion molecule 5 , CD66e , CEA

Cellular Localization

Cell membrane,Apical cell membrane

Background

The CEA gene family belongs to the immunoglobulin gene superfamily (IgSF) and comprises a large number of genes. The cell surface associated CEA proteins are heavily glycosylated, abundantly expressed and multifunctional. The human carcinoembryonic antigen (CEA) family can be divided into two subgroups according to the means of anchorage of member glycoproteins to the cell membrane: glycophosphatidyl inositol (GPI) linkage and transmembrane linkage. GPI-linked CEA family members include CEA (CD66e), non-specific cross-reacting antigen (NCA, CD66c), CEA gene-family members 6 (CGM6, CD66b) and 2 (CGM2). Transmembrane-linked members include biliary glycoprotein (BGP, Human C-CAM-L and C-CAM-S, CD66a), CGM1(CD66d) and CGM7. Recent evidence suggests the GPI-linked members tend to be up-regulated in human tumors, whereas the transmembrane-linked members tend to be down-regulated.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519