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CDK4 antibody [DCS-31]

Anti-CDK4 antibody [DCS-31] used in Western Blot (WB). GTX26315

Cat. No. GTX26315

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 DCS-31

Isotype

 IgG2a

Application

 WB, ICC/IF, IHC-P, IP

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CDK4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1,000
ICC/IF Assay dependent
IHC-P Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Positive Control

human melanoma cell, fibrosarcoma cells

Product Note

The antibody reacts specifically with Cdk4 and does not recognize other Cdk types.

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

recombinant human Cdk4 protein

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclin dependent kinase 4 , CMM3 , PSK-J3

Cellular Localization

Cytoplasm,Nucleus,Membrane

Background

Regulation of cell cycle progression in eukaryotic cells depends on the expression of cyclins. These proteins form complexes with several different cyclin dependant kinases (CDKs). Within complexes, the cyclin subunit serves a regulatory role, whereas the CDKs have a catalytic protein kinase activity. Complexes of cyclins and CDKs play a key role in cell cycle control. The eukaryotic cell cycle is regulated by the sequential activation of CDKs.

Database

Research Area

DATA IMAGES

Anti-CDK4 antibody [DCS-31] used in Western Blot (WB). GTX26315

GTX26315 WB Image

WB analysis of HeLa and human uterine mesodermal tumor cell-SKUT lysates using GTX26315 CDK4 antibody [DCS-31].
Dilution : 1:2000

REFERENCE

Clone Reference

Noëlle Weingertner et al. Appl Immunohistochem Mol Morphol 2015; 23 (3):230-5 Myxoid liposarcoma with heterologous components: dedifferentiation or metaplasia? A FISH-documented and CGH-documented case report
Application : IHC-P
Reactivity : Human
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399