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CYP7B1 antibody

Anti-CYP7B1 antibody used in Western Blot (WB). GTX04545
Anti-CYP7B1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04545
Anti-CYP7B1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04545

Cat. No. GTX04545

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all CYP7B1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
ICC/IF 1:50-1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.05% proclin300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human CYP7B1 (NP_004811.1), corresponding to amino acid residues V200-T300.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cytochrome P450 family 7 subfamily B member 1 , CBAS3 , CP7B , SPG5A

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]

Database

Research Area

DATA IMAGES

Anti-CYP7B1 antibody used in Western Blot (WB). GTX04545

GTX04545 WB Image

WB analysis of A431 whole cell lysate using GTX04545 CYP7B1 antibody.
Dilution : 1:1000
Loading : 25 μg

Anti-CYP7B1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04545

GTX04545 ICC/IF Image

ICC/IF analysis of NIH-3T3 cells using GTX04545 CYP7B1 antibody.
Orange : Primary antibody
Blue : DAPI
Dilution : 1:20

Anti-CYP7B1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04545

GTX04545 ICC/IF Image

ICC/IF analysis of PC-12 cells using GTX04545 CYP7B1 antibody.
Orange : Primary antibody
Blue : DAPI
Dilution : 1:20

REFERENCE

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REVIEW

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Package List Price ($)
$ 399