Caspase 6 (cleaved Asp162) antibody

Name: Caspase 6 (cleaved Asp162) antibody
Brand: GeneTex
SKU: GTX134362
Price: 399.00 USD
Rating: 4 (1 reviews)

Anti-Caspase 6 (cleaved Asp162) antibody used in IHC (Paraffin sections) (IHC-P). GTX134362

Anti-Caspase 6 (cleaved Asp162) antibody used in Western Blot (WB). GTX134362

Cat. No. GTX134362

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse, Rat
Package	100 μl ($399), 25 μl ($169)

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Datasheet
Document

View product citations for antibody GTX134362 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:1000
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Predict Reactivity

Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Caspase 6 (cleaved Asp162). The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2887260

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase 6 , MCH2

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]

Database

Gene ID: 839 CASP6
UniProt: P55212 CASP6

Research Area

DATA IMAGES

GTX134362 IHC-P Image

Caspase 6 (cleaved Asp162) antibody detects Caspase 6 (cleaved Asp162) protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
Caspase 6 (cleaved Asp162) stained by Caspase 6 (cleaved Asp162) antibody (GTX134362) diluted at 1:1000.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX134362 IHC-P Image

Caspase 6 (cleaved Asp162) antibody detects Caspase 6 (cleaved Asp162) protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded rat esophagus.
Caspase 6 (cleaved Asp162) stained by Caspase 6 (cleaved Asp162) antibody (GTX134362) diluted at 1:1000.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

GTX134362 WB Image

Untreated (–) and treated (+) Jurkat whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Caspase 6 (cleaved Asp162) antibody (GTX134362) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

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