APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:2000 |
| 1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA, 50% Glycerol
Preservative
0.02% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthesized peptide derived from human CYP2D6.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cytochrome P450 family 2 subfamily D member 6 , CPD6 , CYP2D , CYP2D7AP , CYP2D7BP , CYP2D7P2 , CYP2D8P2 , CYP2DL1 , CYPIID6 , P450-DB1 , P450C2D , P450DB1
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Database
Research Area
DATA IMAGES
![Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703](/templates/default/js/lightbox/images/loading.gif "Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703")
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GTX03703 IHC-P Image
IHC-P analysis of rat liver tissue using GTX03703 Cytochrome P450 2D6 antibody [GT1357].
Dilution : 1:100
Blue : DAPI
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GTX03703 WB Image
WB analysis of various sample lysates using GTX03703 Cytochrome P450 2D6 antibody [GT1357].
Dilution : 1:1000
Loading : 25 μg per lane
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GTX03703 IHC-P Image
IHC-P analysis of mouse liver tissue using GTX03703 Cytochrome P450 2D6 antibody [GT1357].
Dilution : 1:100
Blue : DAPI
|
REFERENCE
There are currently no references for Cytochrome P450 2D6 antibody [GT1357] (GTX03703). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Cytochrome P450 2D6 antibody [GT1357] (GTX03703). Be the first to share your experience with this product.
![Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703](/upload/website/prouct_img/small/GTX03703/GTX03703_20220524_IHC_w_23053123_453.webp "Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703")
![Anti-Cytochrome P450 2D6 antibody [GT1357] used in Western Blot (WB). GTX03703](/upload/website/prouct_img/small/GTX03703/GTX03703_20220524_WB_w_23053123_750.webp "Anti-Cytochrome P450 2D6 antibody [GT1357] used in Western Blot (WB). GTX03703")
![Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703](/upload/website/prouct_img/small/GTX03703/GTX03703_20220524_IHC_1_w_23053123_532.webp "Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703")
![Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703](/upload/website/prouct_img/normal/GTX03703/GTX03703_20220524_IHC_w_23053123_453.webp "Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703")
![Anti-Cytochrome P450 2D6 antibody [GT1357] used in Western Blot (WB). GTX03703](/upload/website/prouct_img/normal/GTX03703/GTX03703_20220524_WB_w_23053123_750.webp "Anti-Cytochrome P450 2D6 antibody [GT1357] used in Western Blot (WB). GTX03703")
![Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703](/upload/website/prouct_img/normal/GTX03703/GTX03703_20220524_IHC_1_w_23053123_532.webp "Anti-Cytochrome P450 2D6 antibody [GT1357] used in IHC (Paraffin sections) (IHC-P). GTX03703")