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GDF15 antibody

Anti-GDF15 antibody used in Immunoprecipitation (IP). GTX54079
Anti-GDF15 antibody used in Western Blot (WB). GTX54079
Anti-GDF15 antibody used in IHC (Paraffin sections) (IHC-P). GTX54079

Cat. No. GTX54079

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP

Reactivity

 Human
Package
100 μl ($399)
See all GDF15 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
IP 1:50 - 1:200
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 49-308 of human GDF15 (NP_004855.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

growth differentiation factor 15 , GDF-15 , MIC-1 , MIC1 , NAG-1 , PDF , PLAB , PTGFB

Cellular Localization

Secreted

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]

Database

Research Area

DATA IMAGES

Anti-GDF15 antibody used in Immunoprecipitation (IP). GTX54079

GTX54079 IP Image

IP analysis of HT-1080 cell lysate using GTX54079 GDF15 antibody.
Antibody amount : 3μg / 200μg lysate
Dilution : 1:1000

Anti-GDF15 antibody used in Western Blot (WB). GTX54079

GTX54079 WB Image

WB analysis of various sample lysates using GTX54079 GDF15 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-GDF15 antibody used in IHC (Paraffin sections) (IHC-P). GTX54079

GTX54079 IHC-P Image

IHC-P analysis of human placenta tissue using GTX54079 GDF15 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399