GeneTex

  • Country / Location Selection

United States (US)

GSK3 beta (phospho Ser9) antibody

Anti-GSK3 beta (phospho Ser9) antibody used in Western Blot (WB). GTX48612

Cat. No. GTX48612

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat, Zebrafish, Bovine, Dog, Chicken, Xenopus, Primate
Package
50 μl ($399)
See all GSK3 beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Product Note

Specific for the ~46k GSK3 beta protein phosphorylated at Ser9. Also weakly labels the ~51k GSK3 alpha band due to the high degree of homology between the 2 subunits. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.

PROPERTIES

Form

Liquid

Buffer

10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Phosphopeptide corresponding to amino acid residues surrounding the phosphoSer9 of GSK3 beta.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glycogen synthase kinase 3 beta

Cellular Localization

Cytoplasm,Nucleus,Cell membrane

Background

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-GSK3 beta (phospho Ser9) antibody used in Western Blot (WB). GTX48612

GTX48612 WB Image

WB analysis of rat cortex tissue lysate using GTX48612 GSK3 beta (phospho Ser9) antibody.
Control : without phospho-peptide
Peptide : with phospho-peptide

REFERENCE

There are currently no references for GSK3 beta (phospho Ser9) antibody (GTX48612). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for GSK3 beta (phospho Ser9) antibody (GTX48612). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Package List Price ($)
$ 399