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HYPB/SETD2 antibody

Anti-HYPB/SETD2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64431
Anti-HYPB/SETD2 antibody used in Western Blot (WB). GTX64431
Anti-HYPB/SETD2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64431

Cat. No. GTX64431

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all HYPB/SETD2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

288 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 803-1103 of human SETD2 (NP_054878.5).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SET domain containing 2, histone lysine methyltransferase , HBP231 , HIF-1 , HIP-1 , HSPC069 , HYPB , KMT3A , LLS , SET2 , p231HBP

Cellular Localization

Nucleus

Background

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-HYPB/SETD2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64431

GTX64431 ICC/IF Image

ICC/IF analysis of C6 cells using GTX64431 HYPB/SETD2 antibody.
Blue : DAPI
Dilution : 1:100

Anti-HYPB/SETD2 antibody used in Western Blot (WB). GTX64431

GTX64431 WB Image

WB analysis of various sample lysates using GTX64431 HYPB/SETD2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-HYPB/SETD2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64431

GTX64431 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX64431 HYPB/SETD2 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399