APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes human IKKα (85 kD). No cross-reactivity with IKKβ or IKKγ.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide corresponding to aa 716-734 of human IKKα which differs from the corresponding murine sequence by four amino acids.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CHUK , IKBKA , IKK1 , IKKA , IKKalpha , NFKBIKA , TCF16 , conserved helixloophelix ubiquitous kinase , IKK alpha , component of inhibitor of nuclear factor kappa B kinase complex
Cellular Localization
Cytoplasm,Nucleus
Background
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for IKK alpha antibody (GTX24111). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IKK alpha antibody (GTX24111). Be the first to share your experience with this product.