APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500-1:1,000 |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes IKKγ (52 kD). No cross-reactivity with IKKα, IKKβ or IKKε.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide corresponding to aa 400-416 of human IKKγ. This sequence is identical to that of mouse.
Purification
Purified by DEAE chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
AMCBX1 , FIP3 , Fip3p , IKBKG , IKKAP1 , IKKG , IKKgamma , IMD33 , IP , IP1 , IP2 , IPD2 , NEMO , ZC2HC9 , inhibitor of kappa light polypeptide gene enhancer in Bcells, kinase gamma , IKK gamma , inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Cellular Localization
Cytoplasm,Nucleus
Background
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016]
Database
Research Area
REFERENCE
There are currently no references for IKK gamma antibody (GTX27890). Be the first to share your publications with this product.
REVIEW
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