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IRS1 (phospho Ser639) antibody

Anti-IRS1 (phospho Ser639) antibody used in Western Blot (WB). GTX38614
Anti-IRS1 (phospho Ser639) antibody used in IHC (Paraffin sections) (IHC-P). GTX38614

Cat. No. GTX38614

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
50 μl ($399)
See all IRS1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

132 kDa. ( Note )

Product Note

This antibody detects endogenous levels of IRS1 only when phosphorylated at serine 639.

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human IRS1 around the phosphorylation site of serine 639 (P -K-S(p)-V-S).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin receptor substrate 1 , HIRS-1

Background

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES

Anti-IRS1 (phospho Ser639) antibody used in Western Blot (WB). GTX38614

GTX38614 WB Image

WB analysis of 293 cell lysate using GTX38614 IRS1 (phospho Ser639) antibody.

Anti-IRS1 (phospho Ser639) antibody used in IHC (Paraffin sections) (IHC-P). GTX38614

GTX38614 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX38614 IRS1 (phospho Ser639) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399