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Integrin beta 1 / CD29 antibody [4B7R]

Cat. No. GTX23167

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4B7R

Isotype

 IgG1

Application

 ICC/IF, IHC-Fr, FACS

Reactivity

 Human, Pig
Package
500 μl ($399)
See all Integrin beta 1 / CD29 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

< 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Human melanoma V+B2 cell line

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_369210

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 1 , CD29 , FNRB , GPIIA , MDF2 , MSK12 , VLA-BETA , VLAB

Cellular Localization

Cell membrane,Cell junction

Background

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Itou J et al. Biochim Biophys Acta 2016; 1864 (1) : 76-88 The Sal-like 4 - integrin α6β1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells.

Clone Reference

Su LJ et al. Sci Rep 2017; 7:45607 Fluorescent nanodiamonds enable quantitative tracking of human mesenchymal stem cells in miniature pigs.
Ueda S et al. J Clin Immunol 2010; 30 (6):861-71 Up-regulation of ?1 integrin on tonsillar T cells and its induction by in vitro stimulation with α-streptococci in patients with pustulosis Palmaris et Plantaris.
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REVIEW

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Package List Price ($)
$ 399