GeneTex
  • Country / Location Selection

United States (US)

MALT1 antibody [MT1/410]

Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812
Anti-MALT1 antibody [MT1/410] used in IHC (Paraffin sections) (IHC-P). GTX34812

Cat. No. GTX34812

Host

Mouse

Clonality

Monoclonal

Clone Name

MT1/410

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($529)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

92 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human MALT1 recombinant fragment (aa701-808)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

IMD12 , MALT1 , MALT1 paracaspase , MLT , MLT1 , PCASP1

Cellular Localization

Cytoplasm,Perinuclear region,Nucleus

Background

This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]

Database

Research Area

DATA IMAGES

Anti-MALT1 antibody [MT1/410] used in Western Blot (WB). GTX34812

GTX34812 WB Image

WB analysis of Daudi cell lysate using GTX34812 MALT1 antibody [MT1/410].

Anti-MALT1 antibody [MT1/410] used in IHC (Paraffin sections) (IHC-P). GTX34812

GTX34812 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX34812 MALT1 antibody [MT1/410].

REFERENCE

There are currently no references for MALT1 antibody [MT1/410] (GTX34812). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for MALT1 antibody [MT1/410] (GTX34812). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529