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Mu Opioid receptor antibody

Anti-Mu Opioid receptor antibody used in Western Blot (WB). GTX17934
Anti-Mu Opioid receptor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX17934
Anti-Mu Opioid receptor antibody used in Western Blot (WB). GTX17934

Cat. No. GTX17934

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, FACS, IHC

Reactivity

 Human, Mouse, Rat, Rabbit
Package
50 μl ($399)
See all Mu Opioid receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:250
ICC/IF 1:250
FACS 1:20
IHC Assay dependent
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA, 50% Glycerol

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against a chemically synthesized peptide derived from an internal region of the human m-opioid receptor.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

opioid receptor mu 1 , LMOR , M-OR-1 , MOP , MOR , MOR1 , OPRM

Cellular Localization

Cell membrane,Cell projection, dendrite,Endosome

Background

This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]

Database

Research Area

DATA IMAGES

Anti-Mu Opioid receptor antibody used in Western Blot (WB). GTX17934

GTX17934 WB Image

WB analysis of rat brain lysates using GTX17934 Mu Opioid receptor antibody.

Anti-Mu Opioid receptor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX17934

GTX17934 ICC/IF Image

ICC/IF analysis of Neuro-2A cells using GTX17934 Mu Opioid receptor antibody. Panel e is a no primary antibody control.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : 4% paraformaldehyde
Permeabilization : 0.1% Triton X-100 for 10 minutes
Dilution : 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature

Anti-Mu Opioid receptor antibody used in Western Blot (WB). GTX17934

GTX17934 WB Image

WB analysis of membrane enriched extracts (30 μg lysate) of Neuro-2a (Lane 1), U-87 MG (Lane 2), IMR-32 (Lane 3), SK-N-AS (Lane 4), U-2 OS (Lane 5) and tissue extracts of Mouse Cerebellum (Lane 6) and Rat Brain (Lane 7) using GTX17934 Mu Opioid receptor antibody.
Dilution : 1:250

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399