APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
2-10 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
ACHN , human fetal pancreas
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to an Internal region of Human NEU1
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
neuraminidase 1 , NANH , NEU , SIAL1
Cellular Localization
Cell membrane,Cytoplasmic vesicle,Lysosome
Background
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX46743 IHC-P Image
IHC-P analysis of human muscle tissue using GTX46743 NEU1 antibody at 4.0-8.0μg/ml.
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GTX46743 WB Image
WB analysis of human fetal pancreas tissue using GTX46743 NEU1 antibody at 5.0μg/ml.
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GTX46743 WB Image
WB analysis of ACHN cells using GTX46743 NEU1 antibody at 1μg/ml.
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REFERENCE
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REVIEW
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