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NPY1R antibody

Anti-NPY1R antibody used in Western Blot (WB). GTX54639

Cat. No. GTX54639

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Mouse, Rodent
Package
100 μl ($399)
See all NPY1R products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide of human NPY1R

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887869

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neuropeptide Y receptor Y1 , NPY1-R , NPYR

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]

Database

Research Area

DATA IMAGES

Anti-NPY1R antibody used in Western Blot (WB). GTX54639

GTX54639 WB Image

WB analysis of mouse fetal brain tissue lysate using GTX54639 NPY1R antibody.
Loading : 25μg per lane

REFERENCE

Application Reference

Clark CM et al. Brain Sci 2021; 11 (8) Differential NPY-Y1 Receptor Density in the Motor Cortex of ALS Patients and Familial Model of ALS.
Spencer B et al. J Biol Chem 2016; 291 (4) : 1905-20 Systemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease.
Application : WB, IHC-P
Reactivity : Rodent
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399