Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
Assay dependent |
20 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Liver Tissue Slide , Human Liver Tissue Lysate
Product Note
This antibody is human specific. At least four isoforms are known to exist. This antibody is predicted to not cross-react with other SLCO1B proteins.
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
OATP2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human OATP2.The immunogen is located within the last 50 amino acids of OATP2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
RRID
AB_2887622
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
solute carrier organic anion transporter family member 1B1 , HBLRR , LST-1 , LST1 , OATP-C , OATP1B1 , OATP2 , OATPC , SLC21A6
Background
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]
Database
Research Area