APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.5-2.5 μg/ml |
0.25 μg/ml |
5-25 μg/ml |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.25 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide selected from the C-terminal region of human PI3Kβ
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
P110BETA , PI3K , PI3KBETA , PIK3C1 , PIK3CB , phosphatidylinositol4,5bisphosphate 3kinase catalytic subunit beta , PI3 Kinase p110 beta , PI3K p110 beta , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Cellular Localization
Cytoplasm,Nucleus
Background
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Database
Research Area
DATA IMAGES
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GTX59597 WB Image
WB analysis of Jurkat cell lysate using GTX59597 PI3 kinase p110 beta antibody, C-term.
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REFERENCE
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REVIEW
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