APPLICATION
Application Note
ELISA: Use at an assay dependant concentration. RIA: Use at an assay dependant concentration. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
Product Note
Human prostate-specific antigen - 100% PSA/alpha-1-ACT-complex - 59%Kallikrein - <0.04% PAP - <0.04% Cross-reactivity values have been calculated on weight/weight basis using 125-I-labelled human human prostate-specific antigen in assay. They can vary because of the presence of antigen or related impurities in protein preparations used for cross reactivity assays.Affinity constant: 1x1011 l/mol human prostate-specific antigen.
PROPERTIES
Form
Liquid
Buffer
NaCl, Citrate-Phosphate
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
5.3 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Full length native protein (purified) (Human)
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
kallikrein related peptidase 3 , APS , KLK2A1 , PSA , hK3
Cellular Localization
Secreted
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for PSA antibody [PSA1] (GTX20403). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PSA antibody [PSA1] (GTX20403). Be the first to share your experience with this product.