PSMA antibody [k1H8]

Cat. No. GTX57558

Host	Mouse
Clonality	Monoclonal
Clone Name	k1H8
Isotype	IgG1
Application	WB, ICC/IF, FACS
Reactivity	Human
Package	100 μl ($399)

See all PSMA products

Datasheet
Document

View product citations for antibody GTX57558 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:1000-1:2000
ICC/IF	Assay dependent
FACS	Assay dependent

Not tested in other applications.

Calculated MW

84 kDa. ( Note )

Observed MW

100 kDa. The observed M.W. is based on the following publication. PMID: 26576996

PROPERTIES

Form

Liquid

Buffer

PBS, 10% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The clone k1H9 is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PSMA protein.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

folate hydrolase 1 , FGCP , FOLH , FOLH1 , GCP2 , GCPII , NAALAD1 , NAALAdase , PSM , PSMA , mGCP

Cellular Localization

Cell membrane,Cytoplasm

Background

This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]

Database

Gene ID: 2346 FOLH1
UniProt: Q04609 FOLH1

Research Area

DATA IMAGES

GTX57558 WB Image

WB analysis of LNCap whole cell lysate using GTX57558 PSMA antibody.
Loading : 30 μg
Dilution : 1:1000

GTX57558 ICC/IF Image

ICC/IF analysis of LNCaP cells using GTX57558 PSMA antibody.
Blue: DAPI
Green: Primary antibody
Dilution: 1:100

GTX57558 FACS Image

FACS analysis of LNCaP cells using GTX57558 PSMA antibody.
Cell Number: 1 x 10⁶ cells
Primary antibody: Red line
Antibody amount: 2-5 μg

REFERENCE

There are currently no references for PSMA antibody [k1H8] (GTX57558). Be the first to share your publications with this product.

Submit a Reference

REVIEW

There are currently no reviews for PSMA antibody [k1H8] (GTX57558). Be the first to share your experience with this product.

Submit a Review

SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 399

Qty