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Pentraxin 3 antibody, N-term

Anti-Pentraxin 3 antibody, N-term used in Western Blot (WB). GTX45054
Anti-Pentraxin 3 antibody, N-term used in Western Blot (WB). GTX45054
Anti-Pentraxin 3 antibody, N-term used in Western Blot (WB). GTX45054
Anti-Pentraxin 3 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX45054
Anti-Pentraxin 3 antibody, N-term used in IHC (Frozen sections) (IHC-Fr). GTX45054
Anti-Pentraxin 3 antibody, N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX45054
Anti-Pentraxin 3 antibody, N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX45054

Cat. No. GTX45054

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, EM

Reactivity

 Human, Mouse
Package
50 μg ($419)
See all Pentraxin 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
ICC/IF Assay dependent
IHC-P 2-10 ug/ml
IHC-Fr Assay dependent
EM Assay dependent
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Positive Control

HepG2 , MCF-7

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human PTX3

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_11170961

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pentraxin 3 , TNFAIP5 , TSG-14

Cellular Localization

Secreted

Background

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]

Database

Research Area

DATA IMAGES

Anti-Pentraxin 3 antibody, N-term used in Western Blot (WB). GTX45054

GTX45054 WB Image

WB analysis of MCF-7 cells using GTX45054 PTX3 antibody at 0.2-1μg/ml.

Anti-Pentraxin 3 antibody, N-term used in Western Blot (WB). GTX45054

GTX45054 WB Image

WB analysis of MCF-7 cells using GTX45054 PTX3 antibody at 1μg/ml.

Anti-Pentraxin 3 antibody, N-term used in Western Blot (WB). GTX45054

GTX45054 WB Image

WB analysis of HepG2 cells using GTX45054 PTX3 antibody at 1.0μg/ml.
Lane A : primary antibody
Lane B : primary antibody + blocking peptide

Anti-Pentraxin 3 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX45054

GTX45054 IHC-P Image

IHC-P analysis of human prostate tissue using GTX45054 PTX3 antibody at 5μg/ml.

Anti-Pentraxin 3 antibody, N-term used in IHC (Frozen sections) (IHC-Fr). GTX45054

GTX45054 IHC-Fr Image

The data was published in the journal PLoS One in 2015. PMID: 25774777

Anti-Pentraxin 3 antibody, N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX45054

GTX45054 ICC/IF Image

The data was published in the journal PLoS One in 2015. PMID: 25774777

Anti-Pentraxin 3 antibody, N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX45054

GTX45054 ICC/IF Image

The data was published in the journal PLoS One in 2015. PMID: 25774777

REFERENCE

Application Reference

Gatto M et al. J Autoimmun 2020; 111 : 102443 Immunization with Pentraxin3 prevents transition from subclinical to clinical lupus nephritis in lupus-prone mice: Insights from renal ultrastructural findings.
Application : ICC/IF, EM
Reactivity : Mouse
Pilling D et al. PLoS One 2015; 10 (3) : e0119709 The long pentraxin PTX3 promotes fibrocyte differentiation.
Application : ICC/IF, IHC-P
Reactivity : Human, Mouse
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419