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RPSA antibody [N2C3]

Anti-RPSA antibody [N2C3] used in Western Blot (WB). GTX113485
Anti-RPSA antibody [N2C3] used in Western Blot (WB). GTX113485
Anti-RPSA antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX113485
Anti-RPSA antibody [N2C3] used in Western Blot (WB). GTX113485

Cat. No. GTX113485

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Zebrafish
Package
100 μl ($399),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

Mouse brain , HeLa , HepG2

Predict Reactivity

Rat, Sheep, Bovine, Dog, Pig, Xenopus tropicalis, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.47 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human RPSA. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2037336

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ribosomal protein SA , 37LRP , 67LR , ICAS , LAMBR , LAMR1 , LBP , LBP/p40 , LRP , LRP/LR , NEM/1CHD4 , SA , lamR , p40

Cellular Localization

Cell membrane , Cytoplasm , Nucleus

Background

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-RPSA antibody [N2C3] used in Western Blot (WB). GTX113485

GTX113485 WB Image

Sample (50 ug of whole cell lysate)
A: mouse brain
12% SDS PAGE
GTX113485 diluted at 1:500

Anti-RPSA antibody [N2C3] used in Western Blot (WB). GTX113485

GTX113485 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
B: Hep G2 (GTX27900)
12% SDS PAGE
GTX113485 diluted at 1:1000

Anti-RPSA antibody [N2C3] used in IHC (Paraffin sections) (IHC-P). GTX113485

GTX113485 IHC-P Image

Immunohistochemical analysis of paraffin-embedded zebrafish tissue, using RPSA antibody [N2C3] (GTX113485) at 1:300 dilution.

Anti-RPSA antibody [N2C3] used in Western Blot (WB). GTX113485

GTX113485 WB Image

Sample (30 μg of whole cell lysate)
A: whole zebrafish
B: zebrafish eye
12% SDS PAGE
GTX113485 diluted at 1:1000

REFERENCE

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169