APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes an epitope included within amino acids 721-733 of STAT1.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
STAT1 peptide sequence 721-733 (DNLLPMSPEEFDE).
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CANDF7 , IMD31A , IMD31B , IMD31C , ISGF3 , STAT1 , STAT91 , signal transducer and activator of transcription 1
Cellular Localization
Cytoplasm,Nucleus
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX23987 WB Image
WB analysis of human malignant melanoma cells (short-term culture derived from a patient) treated with IFN-gamma (10 ng/ml) and IFN-alpha (1000 IU/ml and 5000 IU/ml) using GTX23987 STAT1 antibody [SM1]. Upper Lane : GTX23991 STAT1 (phospho Ser727) antibody [PSM1] Lower Lane : GTX23987 STAT1 antibody [SM1]
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REFERENCE
There are currently no references for STAT1 antibody [SM1] (GTX23987). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for STAT1 antibody [SM1] (GTX23987). Be the first to share your experience with this product.