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Serum Amyloid P antibody

Anti-Serum Amyloid P antibody used in IHC (Paraffin sections) (IHC-P). GTX55792
Anti-Serum Amyloid P antibody used in IHC (Paraffin sections) (IHC-P). GTX55792
Anti-Serum Amyloid P antibody used in Western Blot (WB). GTX55792

Cat. No. GTX55792

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Serum Amyloid P products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human APCS (NP_001630.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

amyloid P component, serum , HEL-S-92n , PTX2 , SAP

Cellular Localization

Secreted

Background

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]

Database

Research Area

DATA IMAGES

Anti-Serum Amyloid P antibody used in IHC (Paraffin sections) (IHC-P). GTX55792

GTX55792 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX55792 Serum Amyloid P antibody.
Dilution : 1:100

Anti-Serum Amyloid P antibody used in IHC (Paraffin sections) (IHC-P). GTX55792

GTX55792 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX55792 Serum Amyloid P antibody.
Dilution : 1:100

Anti-Serum Amyloid P antibody used in Western Blot (WB). GTX55792

GTX55792 WB Image

WB analysis of 293T cell lysate using GTX55792 Serum Amyloid P antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Jiang G et al. J Cell Mol Med 2024; 28 (10) : e18397 SAP deletion promotes malignant insulinoma progression by inducing CXCL12 secretion from CAFs via the CXCR4/p38/ERK signalling pathway.
Wang L et al. J Adv Res 2023; 50 : 55-68 SAP deficiency aggravates periodontitis possibly via C5a-C5aR signaling-mediated defective macrophage phagocytosis of Porphyromonas gingivalis.
Submit a Reference

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399