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TGF beta Receptor 2 antibody

Anti-TGF beta Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37527
Anti-TGF beta Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37527
Anti-TGF beta Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37527
Anti-TGF beta Receptor 2 antibody used in Western Blot (WB). GTX37527

Cat. No. GTX37527

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μg ($459)
See all TGF beta Receptor 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100-2000
IHC-P 1:100-600
Not tested in other applications.

Calculated MW

65 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human TGF beta Receptor 2. Please contact us for the exact immunogen sequence.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transforming growth factor beta receptor 2 , AAT3 , FAA3 , LDS1B , LDS2 , LDS2B , MFS2 , RIIC , TAAD2 , TBR-ii , TBRII , TGFR-2 , TGFbeta-RII

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-TGF beta Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37527

GTX37527 IHC-P Image

IHC-P analysis of rat testis tissue using GTX37527 TGF beta Receptor 2 antibody.
Dilution : 2.5μg/ml

Anti-TGF beta Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37527

GTX37527 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37527 TGF beta Receptor 2 antibody.
Dilution : 2.5μg/ml

Anti-TGF beta Receptor 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX37527

GTX37527 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX37527 TGF beta Receptor 2 antibody.
Dilution : 2.5μg/ml

Anti-TGF beta Receptor 2 antibody used in Western Blot (WB). GTX37527

GTX37527 WB Image

WB analysis of human lung cancer (Lane 1), HeLa cell (Lane 2), 293T cell (Lane 3) lysates using GTX37527 TGF beta Receptor 2 antibody.
Dilution : 1μg/ml

REFERENCE

Application Reference

Khan S et al. Cell Death Dis 2021; 13 (1) : 11 TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy.
Application : WB
Reactivity : Human, Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459