APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
1:5000-1:10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Chickens were immunized with two synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates. These synthetic peptides corresponded to different and nonphosphorylated regions of the Tau gene product, but are shared between the human (NP_05819, NCBI) and mouse (P01637, NCBI) sequences.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
microtubule associated protein tau , DDPAC , FTDP-17 , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU
Cellular Localization
Cytoplasm, cytosol , Cell membrane , Cytoplasm, cytoskeleton , Cytoplasm , Cell projection, dendrite
Background
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX85468 IHC-P Image
IHC-P analysis of neurofibrillary tangles in cortical neurons of an Alzheimer's Disease patient using GTX85468 Tau antibody.
Dilution : 1:10,000
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GTX85468 IHC-P Image
IHC-P analysis of neurofibrillary tangles in cortical neurons of an Alzheimer's Disease patient using GTX85468 Tau antibody.
Dilution : 1:10,000
|
|
GTX85468 IHC-P Image
IHC-P analysis of neurofibrillary tangles in cortical neurons of an Alzheimer's Disease patient using GTX85468 Tau antibody.
Dilution : 1:10,000
|
|
GTX85468 IHC-P Image
IHC-P analysis of neurofibrillary tangles in cortical neurons of an Alzheimer's Disease patient using GTX85468 Tau antibody.
Dilution : 1:10,000
|
REFERENCE
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REVIEW
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