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Tau (phospho Ser198) antibody [EPR2400]

Anti-Tau (phospho Ser198) antibody [EPR2400] used in IHC (Paraffin sections) (IHC-P). GTX62137
Anti-Tau (phospho Ser198) antibody [EPR2400] used in Western Blot (WB). GTX62137

Cat. No. GTX62137

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 EPR2400

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP

Reactivity

 Human
Package
100 μl ($399)
See all Tau products

APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at a dilution of 1:50,000 - 100,000
For IHC: Use at a dilution of 1:100 - 250
For ICC: Use at a dilution of 1:50 - 100
For IP: Use at a dilution of 1:50
Optimal working dilution for a specific application should be determined by the investigator.

Calculated MW

79 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

50mM Tris-Glycine, 150mM NaCl, 0.05% BSA, 40% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A phospho-specific peptide corresponding to residues surrounding serine 198 of human Tau was used as an immunogen.

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,488.

TARGET

Synonyms

microtubule associated protein tau , DDPAC , FTDP-17 , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU

Cellular Localization

Cytoplasm, cytosol , Cell membrane , Cytoplasm, cytoskeleton , Cytoplasm , Cell projection, dendrite

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Tau (phospho Ser198) antibody [EPR2400] used in IHC (Paraffin sections) (IHC-P). GTX62137

GTX62137 IHC-P Image

B. Immunohistochemical analysis of paraffin-embedded human brain tissue using Phospho-specific anti-Tau RabMAb (cat. # GTX62137).

Anti-Tau (phospho Ser198) antibody [EPR2400] used in Western Blot (WB). GTX62137

GTX62137 WB Image

A. Western blot analysis on SH-SY5Y cell lysates using anti-Phospho-Tau (pS198) RabMAb (cat. #GTX62137) 1:100000 dilution. Cells were either (A) untreated (B) treated with AP.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399