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TrkA antibody [6B2]

Anti-TrkA antibody [6B2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83268
Anti-TrkA antibody [6B2] used in Western Blot (WB). GTX83268

Cat. No. GTX83268

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6B2

Isotype

 IgG1

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Rat
Package
100 μl ($399)
See all TrkA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neurotrophic receptor tyrosine kinase 1 , MTC , TRK , TRK1 , TRKA , Trk-A , p140-TrkA

Cellular Localization

Cell membrane

Background

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TrkA antibody [6B2] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83268

GTX83268 ICC/IF Image

ICC/IF analysis of PC12 cells using GTX83268 TrkA antibody [6B2].
Green : TrkA
Blue: DRAQ5 fluorescent DNA dye

Anti-TrkA antibody [6B2] used in Western Blot (WB). GTX83268

GTX83268 WB Image

WB analysis of extracellular domain of human TrkA(aa33-423) using GTX83268 TrkA antibody [6B2].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399