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UFD1L antibody

Anti-UFD1L antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33570
Anti-UFD1L antibody used in Western Blot (WB). GTX33570

Cat. No. GTX33570

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all UFD1L products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human UFD1L (NP_005650.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887721

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ubiquitin recognition factor in ER associated degradation 1 , UFD1L

Cellular Localization

Nucleus,Cytoplasm, cytosol

Background

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

Database

Research Area

DATA IMAGES

Anti-UFD1L antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33570

GTX33570 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX33570 UFD1L antibody.

Anti-UFD1L antibody used in Western Blot (WB). GTX33570

GTX33570 WB Image

WB analysis of various sample lysates using GTX33570 UFD1L antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Li S et al. Nat Commun 2019; 10 (1) : 1693 Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399