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VEGF Receptor 2 antibody [4B4]

Anti-VEGF Receptor 2 antibody [4B4] used in Western Blot (WB). GTX83308
Anti-VEGF Receptor 2 antibody [4B4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83308
Anti-VEGF Receptor 2 antibody [4B4] used in Flow cytometry (FACS). GTX83308

Cat. No. GTX83308

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4B4

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all VEGF Receptor 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

152 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant extracellular fragment of human VEGF Receptor 2 (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

kinase insert domain receptor , CD309 , FLK1 , VEGFR , VEGFR2

Cellular Localization

Cell junction,Endoplasmic reticulum,Cytoplasm,Nucleus,Cytoplasmic vesicle

Background

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Database

Research Area

DATA IMAGES

Anti-VEGF Receptor 2 antibody [4B4] used in Western Blot (WB). GTX83308

GTX83308 WB Image

WB analysis of extracellular domain of human KDR (aa20-764) using GTX83308 VEGF Receptor 2 antibody [4B4].

Anti-VEGF Receptor 2 antibody [4B4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83308

GTX83308 ICC/IF Image

ICC/IF analysis of HeLa (left) and HepG2 (right) cells using GTX83308 VEGF Receptor 2 antibody [4B4].
Green : VEGF Receptor 2
Blue: DRAQ5 fluorescent DNA dye

Anti-VEGF Receptor 2 antibody [4B4] used in Flow cytometry (FACS). GTX83308

GTX83308 FACS Image

FACS analysis of HepG2 cells using GTX83308 VEGF Receptor 2 antibody [4B4].
Green : VEGF Receptor 2
Purple : negative control

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399