Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Purification
Purified by precipitation and chromatography
Conjugation
Unconjugated
RRID
AB_425224
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CTRCT30 , HEL113 , VIM , vimentin , Vimentin
Cellular Localization
Cytoplasm
Background
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
IP analysis of HeLa cell lysate using GTX40346 Vimentin antibody [VI-10] . The signal wass detected by GTX27752 Vimentin antibody [VI-01] in WB assay. Lr : Lysate (reducing conditions) Lnr : Lysate (non-reducing conditions) IPr : Immunoprecipitate (reducing conditions) IPnr : Immunoprecipitate (non-reducing conditions)
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GTX40346 ICC/IF Image
ICC/IF analysis of chicken postnatal erythrocytes using GTX40346 Vimentin antibody [VI-10]. Green : Primary antibody Red : Tubulin Blue : DAPI