APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human ACTN1 (NP_001123477.1).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
actinin alpha 1 , BDPLT15
Cellular Localization
Cytoplasm, cytoskeleton,Cell membrane,Cell junction
Background
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX55505 IHC-P Image
IHC-P analysis of mouse heart tissue using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:100
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GTX55505 WB Image
WB analysis of various sample lysates using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:500
Loading : 25μg per lane
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GTX55505 IHC-P Image
IHC-P analysis of human liver cancer tissue using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:100
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GTX55505 IHC-P Image
IHC-P analysis of human esophagus tissue using GTX55505 alpha Actinin 1 antibody.
Dilution : 1:100
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REFERENCE
There are currently no references for alpha Actinin 1 antibody (GTX55505). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for alpha Actinin 1 antibody (GTX55505). Be the first to share your experience with this product.
