APPLICATION
Application Note
Recommended Starting Dilutions:
For IHC: Use at 1:100
Optimal dilutions should be determined experimentally by the researcher.
Calculated MW
Product Note
S-arrestin in retina from porcine, human, bovine & weakly with rat, and shows heteroclitic behaviour
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Pig
Immunogen
Porcine S-antigen
Purification
Protein G
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
S-antigen visual arrestin , RP47 , S-AG
Cellular Localization
Membrane
Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for S-arrestin antibody [PDS-1] (GTX40621). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for S-arrestin antibody [PDS-1] (GTX40621). Be the first to share your experience with this product.