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5-HT2A receptor antibody

Anti-5-HT2A receptor antibody used in Western Blot (WB). GTX04873
Anti-5-HT2A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX04873

Cat. No. GTX04873

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all 5-HT2A receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:3000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Predict Reactivity

Rat, Rabbit, Sheep, Bovine, Dog, Pig, Horse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human HTR2A(Accession P28223), corresponding to amino acid residues I252-E302.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

HTR2,HTR2A,Serotonin receptor 2A,SR-2A,5HT2A,5hydroxytryptamine receptor 2A,5HT2A Receptor,5-HT2A receptor,5-hydroxytryptamine receptor 2A

Cellular Localization

Cell membrane,Cell projection,Dendrite,Axon,Cytoplasmic vesicle,Membrane,Caveola

Background

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-5-HT2A receptor antibody used in Western Blot (WB). GTX04873

GTX04873 WB Image

WB analysis of COLO205 whole cell lysate using GTX04873 5-HT2A receptor antibody.

Anti-5-HT2A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX04873

GTX04873 IHC-P Image

IHC-P analysis of human brain tissue using GTX04873 5-HT2A receptor antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 399