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Acetyl-CoA Carboxylase 1 antibody

Anti-Acetyl-CoA Carboxylase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54946
Anti-Acetyl-CoA Carboxylase 1 antibody used in Western Blot (WB). GTX54946

Cat. No. GTX54946

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Acetyl-CoA Carboxylase 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

266 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of Acetyl-CoA Carboxylase 1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

acetyl-CoA carboxylase alpha , ACAC , ACACAD , ACC , ACC1 , ACCA

Cellular Localization

Cytoplasm

Background

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 31 ACACA
  • UniProt: Q13085 ACACA

Research Area

DATA IMAGES

Anti-Acetyl-CoA Carboxylase 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54946

GTX54946 IHC-P Image

IHC-P analysis of formalin fixed human colon cancer tissue section using GTX54946 Acetyl-CoA Carboxylase 1 antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-Acetyl-CoA Carboxylase 1 antibody used in Western Blot (WB). GTX54946

GTX54946 WB Image

WB analysis of HepG2 (A), NIH3T3 (B) whole cell lysates using GTX54946 Acetyl-CoA Carboxylase 1 antibody.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399