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CD45RB antibody [PTPRC/2877R]

Anti-CD45RB antibody [PTPRC/2877R] used in IHC (Paraffin sections) (IHC-P). GTX02760
Anti-CD45RB antibody [PTPRC/2877R] used in Western Blot (WB). GTX02760
Anti-CD45RB antibody [PTPRC/2877R] used in Flow cytometry (FACS). GTX02760
Anti-CD45RB antibody [PTPRC/2877R] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX02760
Anti-CD45RB antibody [PTPRC/2877R] used in Western Blot (WB). GTX02760

Cat. No. GTX02760

Host

Rabbit

Clonality

Monoclonal

Clone Name

PTPRC/2877R

Isotype

IgG

Application

WB, ICC/IF, IHC-P, FACS

Reactivity

Human
Package
100 μg ($529)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
ICC/IF 1-2 μg/ml
IHC-P 1-2 μg/ml
FACS 1-2 μg/million cells

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

147 kDa. ( Note )

Observed MW

200-220 kDa. The observed M.W. is based on the following publication. PMID: 16352531

Product Note

We do not recommend use of this product for Rat,Rhesus Monkey samples.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human CD45RB protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-CD45RB antibody [PTPRC/2877R] used in IHC (Paraffin sections) (IHC-P). GTX02760

GTX02760 IHC-P Image

IHC-P analysis of human lymph node tissue section using GTX02760 CD45RB antibody [PTPRC/2877R].

Anti-CD45RB antibody [PTPRC/2877R] used in Western Blot (WB). GTX02760

GTX02760 WB Image

WB analysis of Raji whole cell lysate using GTX02760 CD45RB antibody [PTPRC/2877R].

Anti-CD45RB antibody [PTPRC/2877R] used in Flow cytometry (FACS). GTX02760

GTX02760 FACS Image

FACS analysis of PFA-fixed Raji cells using GTX02760 CD45RB antibody [PTPRC/2877R].
Blue : Primary antibody
Red : Isotype control

Anti-CD45RB antibody [PTPRC/2877R] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX02760

GTX02760 ICC/IF Image

ICC/IF analysis of PFA-fixed Raji cells using GTX02760 CD45RB antibody [PTPRC/2877R].
Green : Primary antibody
Red : Phalloiden (membrane)

Anti-CD45RB antibody [PTPRC/2877R] used in Western Blot (WB). GTX02760

GTX02760 WB Image

WB analysis of human spleen tissue lysate using GTX02760 CD45RB antibody [PTPRC/2877R].

REFERENCE

There are currently no references for CD45RB antibody [PTPRC/2877R] (GTX02760). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD45RB antibody [PTPRC/2877R] (GTX02760). Be the first to share your experience with this product.
Package List Price ($)
$ 529