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CD64 antibody [10.1] (Low Endotoxin)

Cat. No. GTX00467-00

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10.1

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, Functional Assay

Reactivity

 Human, Primate
Package
100 μg ($399)
See all CD64 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
Functional Assay Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Product Note

This antibody recognizes alpha subunit of CD64/FcgammaRI.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rheumatoid synovial fluid cells and fibronectin purified human monocytes

Purification

Protein A purified

Endotoxin

< 0.01 EU/μg (determined by the LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD64 , CD64A , FCGR1A , FCRI , Fc fragment of IgG receptor Ia , IGFR1

Cellular Localization

Cell membrane

Background

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

Yun-Jong Park et al. PLoS Pathog 2022; 18 (4):e1010468 D-dimer and CoV-2 spike-immune complexes contribute to the production of PGE2 and proinflammatory cytokines in monocytes.
Richards JO et al. Mol Cancer Ther 2008; 7 (8):2517-27 Optimization of antibody binding to FcgammaRIIa enhances macrophage phagocytosis of tumor cells.
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations