APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
human fetal brain , human primary myoblasts
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human CNBP
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CCHC-type zinc finger nucleic acid binding protein , CNBP1 , DM2 , PROMM , RNF163 , ZCCHC22 , ZNF9
Cellular Localization
Cytoplasm,Endoplasmic reticulum
Background
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]
Database
Research Area
DATA IMAGES
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GTX44628 WB Image
WB analysis of human fetal brain tissue using GTX44628 CNBP antibody at 0.2-1μg/ml.
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GTX44628 WB Image
WB analysis of human primary myoblasts cells using GTX44628 CNBP antibody at 1:1000.
Lane 1-4 :
1 : myoblasts cell lysate from normal control
2 : myoblasts cell lysate from myotonic dystrophy type 2 patients (DM2)
3 : myoblasts cell lysate from myotonic dystrophy type 2 patients (DM2)
4 : myoblasts cell lysate from myotonic dystrophy type 2 patients (DM2)
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REFERENCE
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REVIEW
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