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CSK antibody [CSK-04]

Anti-CSK antibody [CSK-04] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX14996

Cat. No. GTX14996

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CSK-04

Isotype

 IgG1

Application

 WB, ICC/IF, IP

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all CSK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Product Note

This antibody reacts with Csk (C-terminal Src kinase).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Bacterially expressed recombinant fragment of human Csk corresponding to aa 330-450.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CSK , csrc tyrosine kinase , C-terminal Src kinase

Cellular Localization

Cytoplasm,Cell membrane

Background

The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-CSK antibody [CSK-04] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX14996

GTX14996 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX14996 CSK antibody [CSK-04].
Green : Primary antibody
Red : Actin
Blue : DAPI

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399